AI company TIIM Healthcare is granted an exclusive IP for Duke-NUS sepsis treatment technology

TIIM Healthcare, an AI health technology company in Singapore, has received an exclusive IP license to commercialize a new technology developed by Duke-NUS Medical School to identify patients at risk of death from sepsis.

Founded in 2016, TIIM, which stands for Technology Innovation in Medicine, develops AI classification solutions. Its flagship product, aiTRIAGE, combines both the ability to alter heart rate and common vital signs to identify patients at risk for major adverse cardiac events.


Duke-NUS technology applies a new scoring system that also uses HRV, HRnV, vital signs, and rapid sequential organ failure assessment to predict mortality on admission in infected patients sepsis in the emergency department. This solution does not require a blood test and it can provide a risk assessment within 10 minutes – can be used to continuously monitor the risk of death in patients with sepsis treated. .

The technology was developed using data obtained from approximately 340 sepsis patients in the emergency department of Singapore General Hospital. Based on a research published last year in the peer-reviewed journal PLOS One, its predictive model outperforms existing sepsis risk scoring models.


Every year, sepsis affects more than 50 million people worldwide, resulting in about five million deaths in both adults and children. In Singapore, sepsis caused by pneumonia and urinary tract infections claimed the lives of nearly 5,000 people in 2019.

Currently, conducting a blood test is the most accurate way to assess a patient’s risk of death from sepsis. However, results can take two to four hours, which can delay the delivery of appropriate treatment.

Professor Marcus Ong, director of the Health Services & Systems Research Program at Duke-NUS Medical School and senior author of the study program. Using new sepsis triage technology, EDs can effectively redirect limited but necessary hospital resources to prevent high-risk patients from developing septic shock.

Meanwhile, TIIM Healthcare plans to integrate new technology into its platform to help enhance the accuracy and analytical capabilities of clinicians in handling infectious patients.


In Australia, AI has also been used to develop a tool that can quickly assess the severity and risk of death in patients with sepsis. Developed by eHealth NSW, the AI-powered sepsis risk tool was trained using previous patient data to provide a risk score for sepsis patients. Most recent, Westmead Hospital began testing the technology in its ED lounges.

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