World

Covid-19 news: Valneva reports positive results from vaccine trial

New Scientist Default Image

Commuters on the London Underground

Man Bell/Shutterstock

Newest coronavirus information as of 12pm on 19 October

The UK faces “difficult” months forward, Downing Avenue has warned because the nation’s day by day case numbers method 50,000 for the primary time since July. Figures from the Workplace for Nationwide Statistics present coronavirus an infection ranges in England are getting near the height seen on the top of the second wave and are principally being pushed by infections amongst schoolchildren.

“We at all times knew the approaching months can be difficult,” the prime minister’s spokesman mentioned. “What we’re seeing is case charges, hospitalisations and deaths nonetheless broadly in keeping with the modelling as set out just a few months again now. The vaccination programme will proceed to be our first line of defence, together with new remedies, testing and public well being recommendation. However we’ll clearly preserve an in depth watch on instances.”

Neil Ferguson, an epidemiologist at Imperial Faculty London and member of the federal government’s Scientific Advisory Group for Emergencies (SAGE), instructed BBC Radio 4’s Right now programme that one other lockdown is unlikely, however urged warning. “Folks must be conscious that we’ve at present larger ranges of an infection locally than we’ve virtually ever had in the course of the pandemic,” he mentioned. “For the final three or 4 months we’ve been up at nicely over 1 per cent of the inhabitants contaminated at any time limit.”

Ferguson steered waning immunity is one motive why the UK has larger an infection charges than different European nations that started vaccine rollouts in a while, and mentioned it’s “vital” that we speed up the booster programme, in addition to vaccination for youngsters.

Different coronavirus information

A non-public laboratory suspected of issuing over 40,000 false damaging outcomes for covid-19 PCR exams was not absolutely accredited to carry out the work, opposite to statements by well being officers, The Guardian has reported. The UK Well being Safety Company (UKHSA) introduced on Friday that it was investigating Immensa Well being Clinics Ltd, which has obtained almost £170 million in test-and-trace contracts since being arrange in Might 2020. Each the UKHSA and a authorities spokesperson mentioned the lab had been absolutely accredited earlier than being appointed. However UKAS, the UK accreditation physique, instructed The Guardian that neither Immensa Well being Clinicas Ltd nor its sister firm, Dante Labs, has ever been accredited by the service.

The US Meals and Drug Administration is planning to permit booster photographs from a unique producer to an individual’s authentic vaccination, in accordance with The New York Occasions. Final month the FDA authorised booster doses of the Pfizer/BioNTech vaccine for some teams, however solely for individuals who had beforehand obtained that vaccine. The company is anticipated to approve Moderna and Johnson & Johnson vaccines to be given as boosters this week, and can permit a “mix-and-match” method to allow larger flexibility, the newspaper experiences.

Dashboard: Use our covid-19 dashboard to remain updated with deaths, instances, and vaccination charges all over the world.

Important details about coronavirus

The place did coronavirus come from? And different covid-19 questions answered

What’s covid-19?

Covid-19 vaccines: Every thing you should know in regards to the main photographs

Lengthy covid: Do I’ve it, how lengthy will it final and might we deal with it?

What’s the fairest solution to share covid-19 vaccines all over the world?

Covid-19: The story of a pandemic

What to learn, watch and take heed to about coronavirus

New Scientist Weekly options updates and evaluation on the most recent developments within the covid-19 pandemic. Our podcast sees knowledgeable journalists from the journal talk about the largest science tales to hit the headlines every week – from know-how and house, to well being and the atmosphere.

The Leap is a BBC Radio 4 sequence exploring how viruses can cross from animals into people to trigger pandemics. The primary episode examines the origins of the covid-19 pandemic.

Why Is Covid Killing Folks of Color? is a BBC documentary, which investigates what the excessive covid-19 loss of life charges in ethnic minority sufferers reveal about well being inequality within the UK.

Panorama: The Race for a Vaccine is a BBC documentary in regards to the inside story of the event of the Oxford/AstraZeneca vaccine in opposition to covid-19.

Race Towards the Virus: Hunt for a Vaccine is a Channel 4 documentary which tells the story of the coronavirus pandemic by way of the eyes of the scientists on the frontline.

The New York Occasions is assessing the progress in growth of potential drug remedies for covid-19, and rating them for effectiveness and security.

People of COVID-19 is a venture highlighting the experiences of key employees on the frontline within the combat in opposition to coronavirus within the UK, by way of social media.

Stomach Mujinga: Trying to find the Fact is a BBC Panorama investigation of the loss of life of transport employee Stomach Mujinga from covid-19, following experiences she had been coughed and spat on by a buyer at London’s Victoria Station.

Coronavirus, Defined on Netflix is a brief documentary sequence analyzing the coronavirus pandemic, the efforts to combat it and methods to handle its psychological well being toll.

COVID-19: The Pandemic that By no means Ought to Have Occurred, and How one can Cease the Subsequent One by Debora Mackenzie is about how the pandemic occurred and why it should occur once more if we don’t do issues in a different way in future.

The Guidelines of Contagion is in regards to the new science of contagion and the shocking methods it shapes our lives and behavior. The creator, Adam Kucharski, is an epidemiologist on the London Faculty of Hygiene and Tropical Medication, UK, and within the guide he examines how illnesses unfold and why they cease.

Earlier updates

New Scientist Default Image

A employee on the Valneva laboratories in Vienna, Austria

Akos Stiller/Valneva SE

18 October

Valneva vaccine reveals good outcomes as compared with AstraZeneca jab

A covid-19 vaccine made by Valneva produced stronger antibody responses and fewer uncomfortable side effects than the Oxford/AstraZeneca vaccine in a medical trial, the French firm has introduced. The trial included greater than 4600 individuals within the UK, who have been randomly allotted one of many two vaccines, whereas delta was the predominant coronavirus variant in circulation. The speed of covid-19 instances was comparable within the two teams and no individuals developed extreme sickness from covid-19.

Valneva’s experimental vaccine, VLA2001, consists of inactivated entire virus particles, together with two adjuvants – medication given to enhance the immune response. “It is a far more conventional method to vaccine manufacture than the vaccines thus far deployed within the UK, Europe and North America and these outcomes counsel this vaccine candidate is on observe to play an essential function in overcoming the pandemic,” mentioned Adam Finn on the College of Bristol, UK, chief investigator for the trial, in a press launch.

Final month, the UK authorities scrapped an order for 100 million doses of Valneva’s vaccine, with well being secretary Sajid Javid later telling MPs it had been clear the vaccine “wouldn’t get approval” by the Medicines and Healthcare merchandise Regulatory Company within the UK. Valneva mentioned on 13 September that the UK authorities served discover over allegations of a breach of the provision settlement, which the corporate strenuously denied.

Different coronavirus information

Lockdown measures will stay in place in Auckland, New Zealand, for 2 extra weeks, prime minister Jacinda Ardern has introduced. The nation’s largest metropolis has been beneath extreme restrictions since mid-August in an effort to comprise an outbreak of the delta variant. Earlier this month, Ardern introduced plans for a transition out of lockdown, however mentioned as we speak that restrictions can be wanted for some time longer. “Any interim easing of restrictions… won’t work in direction of our plan of minimising instances whereas we improve vaccinations,” she instructed a information convention.

Hundreds of youngsters have returned to high school in Sydney, Australia, for the primary time in months as a tranche of covid-19 restrictions have been eased within the metropolis. The vaccination fee within the state of New South Wales reached 80 per cent, enabling the following stage of relaxations to go forward beneath the nationwide covid-19 technique. Many retailers and companies can now reopen with capability limits to permit social distancing. In Melbourne, a stay-at-home order that has lasted 73 days will likely be lifted subsequent Friday with the vaccination fee within the state of Victoria on account of go 70 per cent.

New Scientist Default Image

A coronavirus testing laboratory.

JANE BARLOW/POOL/AFP through Getty Photographs

15 October

Operations suspended at Wolverhampton testing lab after investigation

An estimated 43,000 folks could have been given false damaging outcomes on covid-19 PCR exams, the UK Well being Safety Company has mentioned. NHS Take a look at and Hint has suspended testing operations supplied by Immensa Well being Clinic Ltd at its laboratory in Wolverhampton following an investigation into experiences of individuals receiving damaging PCR check outcomes after they’ve beforehand examined optimistic on a lateral move check.

Samples that may have gone to the lab are actually being redirected to others. “There isn’t any proof of any faults with LFD [lateral flow] or PCR check kits themselves and the general public ought to stay assured in utilizing them and in different laboratory companies at present supplied, mentioned Will Welfare, public well being incident director at UKHSA. 

The errors relate to check outcomes given to folks between 8 September and 12 October, primarily within the southwest of England. It’s estimated that round 400,000 samples have been processed by way of the lab. A full investigation is being carried out into why incorrect outcomes got, NHS Take a look at and Hint mentioned. It’s now contacting the individuals who may nonetheless be infectious to advise them to take one other check. Shut contacts who’re symptomatic can even be suggested to take a check, as is already advisable.

Issues have additionally been recognized on the Newbury Showground testing web site in Berkshire. West Berkshire Council mentioned some damaging outcomes could have been given incorrectly. Anybody who obtained a damaging end result on the web site between 3 and 12 October has been urged to take one other check.

Different coronavirus information

People who find themselves taking statins could also be much less more likely to die from coronavirus than comparable folks not on the remedy, analysis suggests. Statins are a standard remedy prescribed for reducing ldl cholesterol within the blood. The analysis, revealed in PLOS Medication, analysed knowledge from 963,876 residents of Stockholm over the age of 45 between March and November 2020. It discovered that statin remedy was related to a barely decrease threat of dying from covid-19. It’s unclear whether or not the statins themselves trigger a decrease loss of life fee, or if different components are accountable.

Charities have known as the rollout of booster vaccines for folks with compromised immune programs within the UK “a chaotic failure”, with lower than half of these eligible contacted thus far. Surveys by Blood Most cancers UK and Kidney Care UK discovered that between 55 and 60 per cent of each affected person teams have but to be invited for a 3rd dose. “It’s now clear that the rollout of the third doses for the immunocompromised has been a failure that was poorly deliberate and badly applied,” mentioned Gemma Peters, chief govt for Blood Most cancers UK.

Newest on coronavirus from New Scientist

Lengthy covid clinics: There are an estimated 706,000 folks in England with lengthy covid signs, and solely 89 specialist clinics set as much as assist them. Assist teams concern that capability could also be stretched if there may be one other giant peak in instances this winter.

New Scientist Default Image

A covid-19 cell fast testing centre.

Maureen McLean/Shutterstock

14 October

Lateral move exams are extra correct than first thought, evaluation suggests

Constructive outcomes on lateral move exams needs to be trusted when ranges of covid-19 within the inhabitants are excessive, say researchers after a brand new evaluation of the exams’ accuracy. 

Lateral move (LF) exams, which might be carried out at dwelling and provides fast outcomes, are thought-about much less dependable than PCR exams achieved in a laboratory. Nevertheless, the exams measure various things: LF exams detect materials from the floor proteins of the virus and determine people who find themselves more likely to be infectious, whereas PCR exams detect genetic materials from the virus which may stay within the physique for weeks after somebody is infectious. This implies it’s anticipated that LF exams won’t determine all the identical instances as PCR exams, so a like-for-like comparability is inappropriate, says Irene Peterson at College Faculty London.

Utilizing a brand new formulation to evaluate the exams’ sensitivity, Peterson and her colleagues discovered that LF exams are greater than 80 per cent efficient at detecting any degree of covid-19 an infection and more likely to be greater than 90 per cent efficient at detecting who’s most infectious once they take the check.

UK authorities steering says that individuals who check optimistic on LF exams ought to have the end result confirmed with a follow-up PCR check, however this isn’t needed, Peterson steered to BBC Information.

The discovering has implications for experiences of an rising variety of people who find themselves testing optimistic in lateral move exams after which getting damaging PCR exams. There may be concern that these damaging PCR outcomes are giving false reassurance to people who find themselves at present infectious (see yesterday’s replace).

Different coronavirus information

Coronavirus infections have been rising exponentially amongst 5 to 17-year-olds in England in September, coinciding with the beginning of the autumn college time period. The newest outcomes from the React-1 research, based mostly on greater than 100,000 swabs from a random pattern of the inhabitants, present that the general prevalence of the virus has remained steady, with one in 120 folks contaminated between 9 and 27 September. Nevertheless, the an infection fee grew amongst these aged beneath 18, and fell amongst these aged 18-54. The information additionally present that for vaccinated folks, the danger of an infection will increase greater than three months after vaccination. This discovering “reinforces the necessity for a booster programme”, research chief Paul Elliott at Imperial Faculty London instructed The Guardian

The World Well being Group (WHO) has introduced a brand new crew of 26 scientists charged with investigating the origins of the covid-19 pandemic. Its preliminary investigation concluded in March 2021 that the virus was in all probability transmitted from bats to people through one other animal, however mentioned extra analysis was wanted. The brand new Scientific Advisory Group for the Origins of Novel Pathogens (Sago) will overview what’s already identified and assess what additional research needs to be undertaken. “That is our greatest probability, and it could be our final probability to know the origins of this virus,” mentioned Mike Ryan, govt director of the WHO Well being Emergencies Programme. Nevertheless, Chen Xu, China’s Ambassador to the UN, mentioned the outcomes of the preliminary research have been “fairly clear” and groups needs to be despatched to different locations.

New Scientist Default Image

A hand dripping a pattern and check answer onto a lateral move check.

David Gee / Alamy Inventory Picture

13 October

UK authorities examine discrepancies between PCR and lateral move exams

The UK Well being Safety Company is investigating experiences of individuals testing optimistic for the coronavirus in lateral move exams however getting damaging outcomes on PCR exams, lots of whom even have signs of covid-19. Below present guidelines, those that have damaging outcomes on PCR exams would not have to self-isolate, however scientists are more and more involved that PCR exams could also be giving false assurances.

PCR exams are usually thought-about to be the “gold customary”, however some research counsel they provide false damaging outcomes to as many as 30-40 per cent of people that even have the virus. Nevertheless, the proportion of lateral move positives that have been confirmed by PCR exams dropped in the newest NHS Take a look at and Hint statistics, suggesting one thing else apart from false PCR negatives is occurring, Oliver Johnson on the College of Bristol instructed The Guardian.

Some have speculated {that a} new variant isn’t getting picked up by PCR exams, however that is thought-about unlikely. Genomic surveillance has not detected a brand new variant and PCR exams goal three components of the viral genome, making it unlikely {that a} new variant may emerge that may have mutations in all three.

One chance is that lateral move exams are responding to a unique seasonal coronavirus. Alternatively, there could also be an issue with the PCR testing course of, resembling a defective batch of reagents.

Different coronavirus information

The US will reopen its land borders with Canada and Mexico for absolutely vaccinated travellers subsequent month. Solely important journey has been permitted because the begin of the pandemic. The US will settle for travellers who’ve been immunised with any of the vaccines permitted by the World Well being Group, not simply these within the US, in accordance with the Facilities for Illness Management and Prevention. Important travellers resembling truck drivers can even need to be vaccinated, however this requirement won’t come into power till January, officers mentioned.

Round one in three UK medical doctors don’t consider their organisation is prepared for the challenges of winter, a medical doctors’ group is warning. A ballot for the Royal Faculty of Physicians discovered that medics additionally felt personally unprepared to take care of upcoming pressures, with many experiencing exhaustion and feeling demoralised. Within the ballot of greater than 800 medical doctors, eight out of 10 of whom have been consultants and most of whom labored within the NHS, 36 per cent mentioned their organisation was by no means ready for winter. Some 27 per cent of medical doctors mentioned they have been personally unprepared, and virtually two-thirds mentioned they have been feeling drained or exhausted. 

New Scientist Default Image

A affected person receives a dose of the Pfizer/BioNtech covid-19 vaccine.

THOMAS COEX/AFP through Getty Photographs

12 October

French research finds three covid-19 vaccines extremely efficient at stopping hospitalisation

Vaccination cuts the danger of dying or being hospitalised with covid-19 by over 90 per cent, in accordance with a French research that’s the largest of its form but. The analysis in contrast 11.3 million vaccinated folks over the age of fifty with the identical variety of age-matched unvaccinated folks between December 2020 and July 2021. The effectiveness was comparable for the Pfizer/BioNTech, Moderna and Oxford/AstraZeneca vaccines, and didn’t diminish in the course of the five-month interval of the research.

The delta variant emerged in France only one month earlier than the tip of the research,  however the outcomes counsel that on this interval, the vaccines have been 84 per cent efficient for these aged 75 and over and 92 per cent efficient for these aged 50 to 74.

Different coronavirus information

Members of parliament have criticised the UK authorities’s response to the covid-19 pandemic in a wide-ranging report revealed as we speak, accusing ministers of adopting a “fatalistic method” to how a lot it may sluggish the unfold of the virus. The report says the federal government made severe errors together with ending neighborhood testing in March 2020, ready too lengthy to implement a lockdown, and permitting contaminated folks to be despatched from hospitals to care properties. Learn our full story for extra particulars. 

The governor of Texas, Greg Abbott, has signed an govt order prohibiting any entity from implementing covid-19 vaccine mandates within the state. The order conflicts with new guidelines being drawn up by the Biden Administration requiring employers with greater than 100 employees to make sure their workers are vaccinated or examined weekly for the virus. 

New Scientist Default Image

JOEL SAGET/AFP through Getty Photographs

11 October

Unvaccinated pregnant ladies make up one in six of probably the most critically ailing covid instances

One in six critically ailing covid-19 sufferers in England are unvaccinated pregnant ladies, in accordance with new figures from July to September. Of the 118 covid-19 sufferers in England who obtained additional corporeal membrane oxygenation (ECMO) throughout this time, 20 of them have been pregnant. ECMO is normally given to critically ailing individuals who haven’t responded to occurring a ventilator.

Of the 20 pregnant ladies who obtained ECMO, only one had been vaccinated – although she had solely obtained one dose, NHS England mentioned. In April, the UK’s Joint Committee on Vaccination and Immunisation suggested that pregnant ladies needs to be provided covid-19 vaccines, ideally the Pfizer/BioNTech or Moderna jabs. 

Out of the opposite 98 individuals who obtained ECMO between July and September, solely seven folks had been absolutely vaccinated, and three had obtained one dose of a vaccine.

Different coronavirus information

The strict lockdown in Sydney, Australia, ended as we speak. Town has had tight restrictions for 4 months in an effort to deal with the delta variant. Over 70 per cent of individuals aged 16 and over are actually absolutely vaccinated, and day by day new an infection numbers are falling.

An infection numbers are rising in New Zealand because the nation continues to ease restrictions. On Sunday 60 new instances of coronavirus have been reported – 56 of them in Auckland. “We’re nonetheless on the knife-edge,” Michael Plank on the College of Canterbury in Christchurch instructed Stuff. The federal government introduced plans to loosen up Auckland’s lockdown final Monday – successfully ending its elimination technique. Consultants concern the virus may unfold out of the town to much less vaccinated populations. 

Covid passports will likely be required in Wales to attend huge occasions or nightclubs from as we speak. They are going to be obligatory for over-18s and can present whether or not individuals are absolutely jabbed or have examined damaging for the virus just lately. Wales’s rugby recreation in opposition to New Zealand on 30 October will likely be one of many first mass occasions to require Covid passes.

New Scientist Default Image

A well being employee administers a second dose of the Pfizer/BioNTech covid-19 vaccine.

Irfan Khan/Los Angeles Occasions/Shutterstock

7 October

Vaccines are as much as 94 per cent efficient over 6 months in individuals who’ve additionally had covid-19

Individuals who have been contaminated with covid-19 after which obtained two vaccine doses have larger immunity in opposition to the virus than those that by no means had a pure an infection.

Figures from customers of the Zoe Covid Symptom Examine App counsel that individuals who obtained two Pfizer/BioNTech jabs after having the sickness noticed a 94 per cent discount of their probabilities of an extra an infection inside six months of their second dose, in contrast with 80 per cent safety for individuals who hadn’t ever had covid-19.

For the AstraZeneca/Oxford vaccine, individuals who’d had covid-19 have been 90 per cent protected, in contrast with 71 per cent in individuals who hadn’t caught it. 

The figures additionally point out that having covid-19, however not getting vaccinated, provides 65 per cent safety in opposition to getting contaminated – and this didn’t wane for as much as 450 days after being contaminated

“That is actually optimistic information for general immunity ranges within the UK and signifies that giant numbers of individuals could have efficient and lengthy lasting safety from covid-19,” Tim Spector at King’s Faculty London, who’s the lead scientist on the Zoe app, mentioned in an announcement. “That is additionally robust proof to help the necessity for vaccination, even for individuals who have already had covid-19.”

Different coronavirus information

Greater than 400,000 folks within the UK say they’ve had lengthy covid for a 12 months or extra, in accordance with new figures from the Workplace for Nationwide Statistics. The most typical signs have been fatigue, shortness of breath, lack of odor and issue concentrating. About 1.1 million folks or 1.7 per cent of the inhabitants have been experiencing self-reported lengthy covid of any period, outlined as signs lasting for greater than 4 weeks after the primary suspected coronavirus an infection.

Nations are speeding to purchase provides of molnupiravir, the primary antiviral drug proven to scale back the danger of extreme covid-19 that may be taken when folks first get contaminated. Australia, Malaysia, South Korea and Singapore have introduced offers to purchase five-day programs of the medication, with Taiwan and Thailand additionally in talks with US-based producer Merck. When taken twice day by day, the drug halves folks’s probabilities of needing hospital remedy or dying.

New Scientist Default Image

Painful purple irritation known as covid toe.

Lakshmiprasad S / Alamy Inventory Picture

6 October

Examine explains why virus could result in pores and skin situation on palms and ft

The pores and skin situation generally known as “covid toe” could also be a facet impact of the immune system’s response to preventing off the virus, a research has discovered. The symptom leads to chilblain-like irritation and redness on the palms and ft, which may final for months at a time. It sometimes develops inside per week to 4 weeks of being contaminated and may end up in toes and fingers changing into swollen or altering color.

Researchers behind the research, which has been revealed within the British Journal of Dermatology, examined 50 individuals with covid toes and 13 with comparable chilblain lesions that arose earlier than the pandemic. They discovered one mechanism behind each sorts of the situation concerned the physique producing an immune response with excessive ranges of sure auto-antibodies, which mistakenly goal and react with an individual’s personal cells and tissues in addition to the invading virus. Additionally they discovered a hyperlink with kind I interferon, a key protein within the antiviral response.

Cells lining blood vessels that provide the affected areas additionally appeared to play a vital function within the growth of covid toes and chilblains.

Covid toe was a standard symptom within the early phases of the pandemic, however has been seen far more not often after vaccination, a spokeswoman for the British Pores and skin Basis instructed BBC Information.

Different coronavirus information

One in seven most cancers sufferers globally had doubtlessly life-saving operations postponed due to the coronavirus pandemic, in accordance with a research revealed within the journal Lancet Oncology. Researchers analysed knowledge on greater than 20,000 sufferers in 61 nations with 15 widespread cancers. Throughout full lockdowns, 15 per cent of sufferers didn’t obtain their deliberate operation for covid-related causes, in comparison with 0.6 per cent during times of “mild restrictions”. The research authors known as for plans to be put in place in order that, within the occasion of one other public well being emergency, pressing surgical procedures can proceed to happen.

Covid passes will likely be required to enter nightclubs and sure giant occasions in Wales after the Welsh Authorities gained a good vote within the Senedd yesterday. From 11 October, the rule will apply to adults attending indoor, non-seated occasions for greater than 500 folks, resembling concert events or conventions, out of doors non-seated occasions for greater than 4000 folks and any setting or occasion with greater than 10,000 folks in attendance. The NHS Covid Go should be used to indicate that somebody is absolutely vaccinated or has had a damaging lateral move check end result inside the final 48 hours.

Newest on coronavirus from New Scientist

New Zealand: Consultants concern the nation’s deliberate transfer away from its “elimination technique” will result in a spike in instances that can overwhelm the well being system.

New Scientist Default Image

Vaccination at a drive-through in Bogotá, Colombia.

Daniel Garzon Herazo/NurPhoto/Shutterstock

5 October

Immunity wanes six months after second dose of Pfizer/BioNTech vaccine

The Pfizer/BioNTech covid-19 vaccine is extremely efficient at stopping hospital admission even with the delta variant, new analysis reveals – although its effectiveness in opposition to an infection virtually halves after six months. Two doses of the jab are 90 per cent efficient in opposition to covid-19 hospital admission for all variants for a minimum of six months, in accordance with the research. However effectiveness in opposition to an infection fell over the research interval, dropping from 88 per cent inside one month of receiving the second dose to 47 per cent after six months.

Researchers analysed greater than 3 million digital well being information from the Kaiser Permanente Southern California well being system between December 2020 and August this 12 months. They discovered that the drop in vaccine effectiveness in opposition to an infection over time might be on account of waning immunity, and never the delta variant escaping the safety provided by the jab.The research, carried out by Kaiser Permanente and Pfizer, is revealed in The Lancet.

Within the UK, Pfizer/BioNTech booster jabs are at present being provided to those that had their second vaccine a minimum of six months in the past and live in residential care properties for older adults, are over 50, or are frontline well being and social care employees. Folks aged 16 to 49 with underlying well being situations that put them at larger threat of extreme signs. and adults who’ve family contact with immunosuppressed people, are additionally being provided third doses.

Different coronavirus information

The European Union’s medicines regulator has advisable that individuals with weakened immune programs ought to have a 3rd dose of Pfizer/BioNTech or Moderna vaccines. The company additionally mentioned a booster shot of this vaccine might be thought-about for adults with regular immune programs round six months after the second dose, however left it to member states to determine whether or not the broader inhabitants ought to get boosters.

AstraZeneca has submitted a request to US regulators to authorise a brand new remedy to stop covid-19 in individuals who have an impaired response to vaccines. The remedy, known as AZD7442, comprises lab-made antibodies designed to remain within the physique for months. Trial outcomes counsel that it cuts the danger of individuals creating any coronavirus signs by 77 per cent, the corporate has reported. 

New Scientist Default Image

New Zealand’s prime minister Jacinda Ardern proclaims plans to ease Auckland’s covid-19 restrictions.

Mark Mitchell – Pool/Getty Photographs

4 October

Vaccine rollout will permit New Zealand to scrap strict lockdowns, says prime minister

New Zealand will shift away from its “zero-covid” technique to 1 during which virus transmission is managed utilizing vaccines, prime minister Jacinda Ardern has introduced.

For the reason that begin of the pandemic, the nation has sought to eradicate the virus by imposing strict lockdown measures in response to any outbreak. The method was largely profitable till August this 12 months, when the arrival of the extra infectious delta variant made it tougher to stamp out transmission. Over 1300 instances have been recorded within the newest outbreak, which started in August.

“With this outbreak and delta, the return to zero is extremely troublesome,” Ardern instructed a information convention as we speak. “It is a change in method we have been at all times going to make over time. Our delta outbreak has accelerated this transition. Vaccines will help it,” she mentioned.

Restrictions will begin to be lifted on Wednesday in Auckland, the nation’s largest metropolis, which has been in lockdown for nearly 50 days. Folks will have the ability to go away their properties and meet outside in teams of as much as 10.

About 2 million folks have been absolutely vaccinated thus far, or 48 per cent of the eligible inhabitants, which is everybody aged 12 and over. Strict lockdowns will finish as soon as 90 per cent of eligible folks have been vaccinated, Ardern mentioned.

Different coronavirus information

An antiviral tablet developed by Merck cuts the danger of hospitalisation or loss of life in covid-19 sufferers by about half, in accordance with interim trial outcomes. The trial concerned 775 adults with delicate to reasonable covid-19 who have been thought-about high-risk for extreme illness. Half of the group got a five-day course of molnupiravir, taken twice a day. The outcomes have been so encouraging that unbiased consultants monitoring the trial advisable that or not it’s stopped early. The corporate will search emergency authorisation from US regulators within the subsequent two weeks. If permitted, the drug can be the primary oral antiviral remedy for covid-19.

New guidelines making it simpler to journey to the UK have come into power as we speak. The visitors mild system involving inexperienced, amber and purple lists has been scrapped, with places categorised as both on the purple record or not. Totally vaccinated residents – and unvaccinated beneath 18s – from greater than 50 nations and territories can now enter the UK with no need to finish a pre-departure lateral move check, take a day-eight post-arrival PCR check, or self-isolate at dwelling, with only a single day-two post-arrival check wanted. Folks arriving from a purple tier vacation spot will nonetheless be required to spend 11 nights at a quarantine resort costing £2,285 for solo travellers.

New Scientist Default Image

A member of the general public receives a Pfizer covid-19 vaccination.

Hugh Hastings/Getty Photographs

1 October

Vaccines for flu and covid-19 can safely be given at similar appointment

It’s protected for folks to get coronavirus and flu vaccines on the similar time, a medical trial has discovered. The reported uncomfortable side effects have been primarily delicate to reasonable and there have been no damaging impacts on the immune response to both vaccine when each got on the identical day, in several arms.

Researchers say the outcomes reinforce present coronavirus booster vaccine steering within the UK, which is for each jabs to be given collectively the place it’s virtually attainable.

The research, involving 679 volunteers in England and Wales, checked out two covid-19 and three flu vaccines, in six completely different mixtures. Examine individuals have been over the age of 18 and had already obtained one dose of both the Pfizer/BioNTech or the Oxford/AstraZeneca jab, and have been awaiting their second dose.

One group obtained their second dose of the covid-19 vaccine and the flu vaccine at their first research go to, then a placebo at their second go to. A second group obtained their second dose of the covid-19 vaccine and a placebo at their first go to after which the flu vaccine at their second go to.

The immune responses to each the flu and covid-19 vaccine have been preserved when given collectively, the outcomes confirmed, and 97 per cent of individuals mentioned they might be prepared to have two vaccines on the similar appointment sooner or later.

The most typical uncomfortable side effects have been ache across the injection web site and fatigue. Some covid-19 and flu vaccine mixtures noticed a rise within the quantity of people that reported a minimum of one facet impact, however the reactions have been principally delicate or reasonable, the analysis discovered.

“It is a actually optimistic step which may imply fewer appointments for individuals who require each vaccines, lowering the burden on those that have underlying well being situations and would normally be provided the influenza vaccine,” mentioned research creator Rajeka Lazarus at College Hospitals Bristol and Weston NHS Basis Belief. The outcomes have been revealed as a preprint in The Lancet.

Different coronavirus information

Scotland’s newly launched vaccine passport app has been hit by technical issues. From as we speak, folks attending giant occasions and nightclubs might want to present proof they’ve had two doses of vaccine utilizing the app earlier than they’re allowed in. The NHS Scotland Covid Standing app was made out there to obtain on Apple and Android gadgets on Thursday afternoon. However simply hours after the app’s launch, feedback circulating on social media steered many customers have been unable to register on it. The Scottish authorities mentioned the big quantity of individuals accessing the app directly might be a motive for the glitch.

Australia will loosen up its guidelines on worldwide journey for residents and everlasting residents in November, having had extreme restrictions in place since March 2020. Folks will likely be allowed to go away the nation as soon as their state’s vaccination fee reaches 80 per cent, prime minister Scott Morrison has mentioned. On returning to Australia, vaccinated residents will likely be allowed to quarantine at dwelling for seven days as a substitute of getting to remain in a resort for 14 days. No timetable has been introduced for opening the border to international travellers. 

Solely 15 out of 54 African nations have met the aim of vaccinating 10 per cent of their inhabitants by the tip of September, the World Well being Group has mentioned. Simply 2 per cent of the greater than 6 billion vaccines given globally have been administered on the continent.

New Scientist Default Image

A youngster receives the Pfizer-BioNTech covid-19 vaccine.

Ian Forsyth/Getty Photographs

30 September

Evaluation helps vaccinating youngsters aged 12 to 17

The advantages of providing two doses of covid-19 vaccine to all youngsters aged 12 to 17 in England clearly outweigh the dangers given the present excessive case charges, in accordance with a brand new evaluation. Youngsters aged 12 to fifteen are at present being provided just one dose of covid-19 vaccine until they’re thought-about excessive threat.

Researchers estimated the covid-19 hospital admissions and deaths, plus instances of lengthy covid, that may be prevented over 4 months by absolutely vaccinating all youngsters on this age group. On 15 September, the case fee amongst 10 to 19-year-olds in England stood at 680 instances per 100,000. If the speed rises to 1000 per 100,000, vaccination may avert 4420 hospital admissions and 36 deaths over a 16-week interval, the research estimated. At a decrease case fee of fifty per 100,000, vaccination may avert 70 admissions and two deaths over the identical interval.

Vaccination would avert between 8000 and 56,000 instances of lengthy covid, the research suggests, assuming that between 2 and 14 per cent of youngsters with covid-19 go on to expertise lengthy covid. The research will likely be revealed as we speak within the Journal of the Royal Society of Medication.

“This evaluation reveals that, on medical dangers alone, vaccination is warranted for 12 to 17-year-olds in England,” mentioned Deepti Gurdasani of Queen Mary College of London, lead creator of the research. “Whereas we wait to know the long-term results of covid-19 on youngsters, the precautionary precept advocates for shielding all youngsters from publicity to this virus and vaccination is a vital a part of that safety.”

The speed of coronavirus transmission within the UK is at present considered highest amongst secondary college age youngsters, with 2.8 per cent on this group testing optimistic in probably the most current figures from the Workplace for Nationwide Statistics on 18 September. 

The UK Joint Committee on Vaccination and Immunisation (JCVI) beforehand determined that, whereas the advantages of vaccination of youngsters aged 12 to fifteen do outweigh the dangers, these advantages aren’t large enough to justify a vaccination programme for this age group. Nevertheless, it wasn’t within the JCVI’s remit to think about how vaccination of 12-to-15-year-olds would forestall college absences or curb the unfold of the virus in communities. Taking components like these under consideration, the UK’s Chief Medical Officers advisable that 12-to-15-year-olds be provided a single dose of the vaccine.

Different coronavirus information

The UK authorities’s furlough scheme, which has helped pay the wages of 11.6 million employees because the begin of the pandemic, is ending as we speak. Practically a million employees have been anticipated to be nonetheless on the scheme on the finish of September, in accordance with the Workplace for Nationwide Statistics. Economists have predicted that the tip of the scheme will result in an increase within the fee of unemployment, which stood at 4.6 per cent final month.

YouTube says it should take away movies that comprise misinformation about all vaccines, increasing its insurance policies round well being misinformation which had been strengthened in the course of the coronavirus pandemic. The Google-owned video platform mentioned its ban on covid-19 vaccine misinformation, which was launched final 12 months, has seen 130,000 movies eliminated thus far because of this, however extra scope is required to clamp down on broader false claims about different vaccines showing on-line. Below the brand new guidelines, any content material which falsely alleges that any permitted vaccine is harmful and causes persistent well being issues will likely be eliminated, as will movies that embrace misinformation in regards to the content material of vaccines.

Newest on coronavirus from New Scientist

Booster vaccines: The proof on coronavirus booster photographs isn’t definitive but, however it suggests you actually ought to get an additional vaccine dose if you’re provided one.

Vaccination technique: Prioritising folks of color for the covid-19 vaccines once they have been briefly provide would have prevented extra deaths than rolling out the vaccine purely by age teams, a US modelling research suggests

New Scientist Default Image

Getty Photographs

29 September

Over a 3rd of individuals recovering from covid-19 have a minimum of one lengthy covid symptom between 3 and 6 months after an infection, a research has discovered. The discovering is predicated on well being information from over 270,000 folks within the US. The most typical reported signs have been nervousness or despair, in 15 per cent of individuals who’d had covid-19, adopted by irregular respiration and belly signs, each seen in 8 per cent, and fatigue, in 6 per cent.

These signs aren’t essentially associated to covid-19, however the research in contrast their prevalence in folks recovering from covid-19 and in individuals who’d had influenza, and located that, collectively, a set of 9 signs have been 1.5 occasions extra widespread after covid-19 than after the flu. Lengthy covid signs have been barely extra widespread in ladies than in males, and extra widespread in those that had been hospitalised.

Makes an attempt to estimate the prevalence of lengthy covid have produced broadly various outcomes, relying on how the situation is outlined and measured. Current figures from the UK Workplace for Nationwide Statistics steered that 11.7 per cent of people that examined optimistic for covid-19 described themselves as experiencing lengthy covid 12 weeks after an infection, however solely 3 per cent skilled signs repeatedly for a minimum of 12 weeks.

Different coronavirus information

Folks receiving a 3rd dose of coronavirus vaccine expertise comparable charges of uncomfortable side effects to these receiving their second dose, in accordance with the US Facilities for Illness Management and Prevention. Out of 12,500 individuals who accomplished a survey, 79 per cent reported native reactions resembling itching or ache on the injection web site, whereas 74 per cent reported systemic reactions, which have been primarily fatigue, muscle aches and complications.

Pfizer and BioNTech have submitted trial knowledge for his or her covid-19 vaccine in 5-to-11-year-olds to the US medicines regulator, and say they are going to make a proper request for emergency authorisation in coming weeks.

The Scottish authorities will delay the enforcement of vaccine passports by two weeks, first minister Nicola Sturgeon has mentioned, giving companies till 18 October to adjust to the brand new legislation. Folks over 18 must present proof of vaccination to attend a nightclub or giant occasion beneath the coverage.

New Scientist Default Image

A pupil receives the Pfizer-BioNTech covid-19 vaccine.

Ian Forsyth/Getty Photographs

28 September

Survey of youngsters in England finds youthful ages extra hesitant about vaccination

Youthful youngsters look like much less prepared to have a covid-19 vaccination than older youngsters, in accordance with a survey of greater than 27,000 college students aged between 9 and 18 in England. Total, half the respondents mentioned they have been prepared to have a coronavirus vaccination, 37 per cent mentioned they have been undecided and 13 per cent mentioned they wished to choose out. Nevertheless, simply over a 3rd of nine-year-olds mentioned they’re prepared to have a covid-19 jab, in contrast with 51 per cent of 13-year-olds and 78 per cent of 17-year-olds.

The survey was carried out in colleges throughout Berkshire, Buckinghamshire, Oxfordshire and Merseyside between Might and July this 12 months by researchers on the College of Oxford, College Faculty London (UCL) and the College of Cambridge. The findings come after 12-to-15-year-olds in England and Scotland final week began to get vaccinated.

Younger individuals who consider they’ve had covid-19 already have been extra more likely to say they are going to choose out of getting a vaccine, the survey discovered. College students who have been extra hesitant about getting the jab have been additionally extra more likely to attend colleges in disadvantaged areas, report spending longer on social media, and say they really feel as if they didn’t determine with their college neighborhood.

Researchers are calling for extra sources and knowledge to be supplied to communities and college students to make sure younger folks know the covid-19 vaccine is protected. They are saying well being messaging about vaccine security and its results on youngsters needs to be shared by trusted sources on social media.

The survey discovered that almost all of kids who mentioned they have been hesitant about getting the vaccine have been nonetheless undecided. “That may be a big alternative for us, however it additionally suggests that there’s threat,” mentioned Russell Viner, a research creator from UCL. “Younger individuals are doubtlessly susceptible to these pushing views which might be very strongly against vaccination.”

Some headteachers have reportedly been focused by hoax letters with misinformation in regards to the vaccine programme, which embrace a faux NHS emblem and a “consent guidelines” to share with college students. A college in Ampthill, Bedfordshire, has apologised for passing the letter on to oldsters in error.

Different coronavirus information

People who smoke are 80 per cent extra more likely to be admitted to hospital and considerably extra more likely to die from covid-19 than non-smokers, new analysis reveals. The research, revealed within the journal Thorax, is the primary of its form to take a look at each observational and genetic knowledge on smoking and coronavirus. It included 421,469 individuals within the UK Biobank research, with consequence knowledge as much as 18 August 2020. The outcomes confirmed that, in contrast with never-smokers, present people who smoke have been twice as more likely to die with covid-19 in the event that they smoked one to 9 cigarettes a day, whereas these smoking 10 to 19 cigarettes a day have been virtually six occasions extra more likely to die. Individuals who smoked greater than 20 a day have been over six occasions extra more likely to die in comparison with individuals who had by no means smoked.

Vaccine passports can be required for these attending nightclubs, music venues, festivals and sports activities grounds in England beneath the federal government’s autumn and winter contingency Plan B. The proposed plan, revealed as we speak, will solely be launched if the nation faces a troublesome winter with rising covid-19 instances within the colder months, the federal government mentioned. The federal government is asking for views from companies, occasion organisers, and venue operators on its proposals by 12 October.

New Scientist Default Image

A mom breastfeeding her son.

Cavan Photographs / Alamy

27 September

Neutralising antibodies in breast milk could defend infants from covid-19 an infection

Breastfeeding ladies who’ve had covid-19 secrete neutralising antibodies in opposition to the virus into their breast milk for as much as 10 months after an infection, in accordance with analysis offered at a convention. Rebecca Powell at Mount Sinai Hospital in New York and her colleagues analysed breast milk samples from 75 ladies who had recovered from a covid-19 an infection. They discovered that 88 per cent of the samples contained antibodies in opposition to the SARS-CoV-2 virus, and most often they have been able to neutralising the virus. 

The findings, offered on the International Breastfeeding and Lactation Symposium on 21 September, counsel that breastfeeding may assist to guard infants from getting contaminated with covid-19. That is identified to be the case for different respiratory illnesses resembling influenza and pertussis. Whereas younger youngsters are at decrease threat from extreme covid-19 than adults, round one in 10 infants under the age of 1 require hospital care if they’re contaminated. Antibodies extracted from breast milk may be used as a remedy for adults with covid-19, Powell instructed The Guardian.

The research additionally discovered that almost all of ladies who had the Pfizer/BioNTech or Moderna vaccines additionally had coronavirus-specific antibodies of their breast milk, however decrease ranges of antibodies have been seen in milk from ladies who had the Johnson & Johnson vaccine. This helps earlier analysis suggesting that vaccinations for breastfeeding moms may help to guard their infants from covid-19 an infection, though this has not but been demonstrated conclusively.

Different coronavirus information

The covid-19 pandemic has led to the largest fall in life expectancy in western Europe because the second world conflict, researchers have discovered. The research, revealed within the Worldwide Journal of Epidemiology, included knowledge from 29 nations, 22 of which noticed a drop in life expectancy that was larger than half a 12 months in 2020. The results have been bigger for males than ladies in most nations. Males within the US noticed the largest fall, with 2.2 years taken off their life expectancy in 2020 in contrast with 2019.

Australian authorities have introduced plans to carry restrictions step by step in Sydney, which has been in lockdown since June. Eating places, retail shops and gymnasiums can start to reopen on 11 October, however solely people who find themselves absolutely vaccinated will likely be allowed to renew procuring, consuming out, and another actions. Round 60 per cent of individuals aged 16 and over are at present absolutely vaccinated within the state of New South Wales.

New Scientist Default Image

Jacob Wackerhausen/Getty Photographs

24 September

Deaths from covid-19 result in drop in life expectancy for boys born in UK

Life expectancy for males within the UK has fallen for the primary time in 4 many years, as a result of impression of the covid-19 pandemic. New figures from the Workplace for Nationwide Statistics (ONS) counsel {that a} boy born between 2018 and 2020 is anticipated to dwell for 79 years, in contrast with 79.2 years for births between 2015 and 2017. For ladies, life expectancy stays unchanged at 82.9 years. The estimates are calculated based mostly on present mortality charges, which have been unusually excessive in 2020, particularly for males.

The figures don’t imply a child born in 2018-2020 will dwell a shorter life, says Pamela Cobb from the ONS Centre for Ageing and Demography. “To get a greater estimate of this we have to take into account how mortality and subsequently life expectancy will enhance into the longer term. It is going to be a number of years earlier than we perceive the impression, if any, of coronavirus on this,” she says.

Different coronavirus information

Covid-19 vaccines have prevented 123,100 deaths in England, in accordance with new estimates. The figures, which have been calculated by Public Well being England and the College of Cambridge, cowl the interval as much as 17 September. Earlier estimates had put the quantity at 112,300 deaths. Round 23.9 million infections have additionally been prevented by the vaccine rollout, together with 230,800 hospital admissions amongst folks aged 45 and over. Greater than 89 per cent of all folks aged 16 and over in England have now obtained a minimum of one dose of vaccine, whereas almost 82 per cent are absolutely vaccinated.

The US Facilities for Illness Management and Prevention (CDC) has endorsed booster vaccines for folks aged 65 and over and people with underlying well being situations, following the authorisation from the Meals and Drug Administration on Wednesday. The CDC’s panel of advisers declined to help booster vaccines for folks in jobs with a excessive threat of publicity to the virus, resembling healthcare employees, however CDC director Rochelle Walensky determined to incorporate this class within the company’s suggestion. The recommendation applies to individuals who have already had two doses of Pfizer/BioNTech covid-19 vaccine a minimum of six months in the past.

New Scientist Default Image

Glass vials containing the BioNTech, Pfizer vaccine.

Ben Hasty/MediaNews Group/Studying Eagle through Getty Photographs

23 September

US regulator authorises boosters for older folks, however rejects broader rollout

The US medicines regulator has authorised coronavirus booster vaccines for folks aged 65 and over, folks at excessive threat of extreme illness and people who are often uncovered to the virus, resembling healthcare employees. The choice signifies that these teams can begin to obtain a 3rd dose of Pfizer/BioNTech vaccine 6 months after their second dose. Those that have had different vaccines must await additional approvals.

Pfizer had requested the Meals and Drug Administration (FDA) to permit additional doses for all folks aged 16 and over, however the FDA panel concluded that there was inadequate proof to help boosters for the broader inhabitants past high-risk teams. A separate advisory committee for the Facilities for Illness Management and Prevention, which determines US vaccine coverage, is anticipated to challenge steering as we speak which can embrace suggestions on which teams ought to qualify as excessive threat. The US has already given additional vaccines to over 2 million folks with compromised immune programs.

Different coronavirus information

The US will donate 500 million extra covid-19 vaccines to different nations, president Joe Biden has introduced at a digital summit on the pandemic, bringing the nation’s whole donations to over 1 billion doses. Supply of the brand new tranche will start in January. At a United Nations Normal Meeting assembly yesterday, leaders from creating nations together with the Philippines, Peru and Ghana condemned wealthier nations for failing to share vaccines equitably.

New journey guidelines for England that require travellers from some nations to quarantine even when they’re absolutely vaccinated have sparked outrage and bewilderment, The Guardian experiences. Below the principles, travellers to England who’ve been absolutely vaccinated with Oxford/AstraZeneca, Pfizer/BioNTech, Moderna or Janssen vaccines within the US, Australia, New Zealand, South Korea or a European Union nation are exempt from quarantine, however individuals who obtained the identical vaccines in different nations should quarantine for 10 days after arrival. Medical doctors and politicians from India, Brazil and Nigeria are amongst those that have expressed anger in regards to the guidelines.

Newest on coronavirus from New Scientist

Winter forecast: A authorities scientific advisory committee has mentioned that the variety of folks in England admitted to hospital with the coronavirus may rise to between 2000 and 7000 a day over the following few months. Right here’s why the predictions for winter are so bleak, regardless of excessive vaccination charges.

New Scientist Default Image

Pupils elevate their palms in a lesson as they return to high school.

Anthony Devlin/Getty Photographs

22 September

Multiple in 100 college youngsters in England have covid-19, however absences are decrease than in July as a result of entire courses not isolate

About 1.2 per cent of college youngsters in England have been absent on account of confirmed or suspected covid-19 on 16 September, in accordance with new figures from the UK’s Division for Training. This compares with 1.0 per cent in July earlier than colleges closed for the summer time holidays. Most faculties reopened in September having eliminated some social distancing restrictions, together with mask-wearing and preserving youngsters inside “bubbles” – small teams normally consisting of 1 or just a few courses. Below this technique the entire bubble would bel despatched dwelling to isolate if one member examined optimistic. Now, under-18s would not have to remain at dwelling and isolate if they’ve been in touch with somebody who has examined optimistic – provided that they themselves develop signs or have a optimistic check end result.

The brand new guidelines imply that whereas there may be at present the next fee of covid-19 infections amongst under-18s, fewer youngsters need to miss college due to isolation guidelines. The overall fee of covid-19-related absences was 1.5 per cent on 16 September, in contrast with 14.3 per cent in July. “These nationwide figures masks some important points arising at a neighborhood degree, and we already know of colleges which might be struggling to maintain courses open on account of outbreaks occurring,” Paul Whiteman, common secretary of the Nationwide Affiliation of Head Lecturers instructed The Guardian.

Different coronavirus information

Australia will reopen its borders for worldwide journey by Christmas on the newest, the nation’s Tourism Minister Dan Tehan mentioned as we speak. In the meantime within the state of Victoria, academics and childcare employees have been instructed that they should be absolutely vaccinated in opposition to covid-19 earlier than they return to work subsequent month.

The Johnson & Johnson “single-dose” covid-19 vaccine is simpler after two doses, the agency mentioned yesterday. A second dose of the jab given eight weeks after the primary led to folks being 94 per cent much less more likely to get a symptomatic an infection in contrast with those that have been unvaccinated, in a US trial. Only one dose was 66 per cent efficient within the first month after vaccination. Giving the second dose six months after the primary led to an even larger rise in antibodies.

See earlier updates from July to September 2021, June to July 2021, Might 2021, April-March 2021, February 2021, January 2021, November/December 2020, and March to November 2020.

Extra on these subjects:

Source link

news7h

News7h: Update the world's latest breaking news online of the day, breaking news, politics, society today, international mainstream news .Updated news 24/7: Entertainment, Sports...at the World everyday world. Hot news, images, video clips that are updated quickly and reliably

Related Articles

Back to top button
Immediate Peak