Health

Drinking too much milk may increase prostate cancer risk

Gary Fraser, MBChB, PhD, the study’s principal investigator and professor at Loma Linda University, said: “Our findings add important weight to other evidence concerning the dairy products rather than non-dairy calcium, Medicine and School of Public Health.

compared with men who consumed only 20.2 grams of milk per day (1/2 cup of milk per week). In addition, men who consumed about 430 grams of milk per day faced an even greater increased risk than men who did not include dairy in their diets.

Fraser noted that the results had the smallest variation when comparing full-fat versus reduced or fat-free milk; No significant associations were reported with cheese and yogurt.

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Fraser and co-authors published the study “Dairy foods, calcium intake, and prostate cancer risk by incident in the Adventist-2 health study,” today in the journal Nature. American Journal of Clinical Nutrition.

The study evaluated the diets of more than 28,000 North American men exposed to a variety of dairy and calcium sources, all of whom were initially cancer-free. Intake was estimated from a food frequency questionnaire (FFQ) and repeated recalls over 24 h. A basic questionnaire included demographics, family history of prostate cancer, physical activity, alcohol consumption, prostate cancer screening, and BMI.

The researchers then used a registry of cancer states to track the participants’ prostate cancer status for an average of nearly eight years. At the end of the study period, state cancer registries reported 1,254 new cases of prostate cancer among the participants during follow-up.

As part of the analysis, Fraser said he and his co-authors separated non-dairy calcium intake (from nuts, seeds, cruciferous and other green vegetables, legumes, fruits, and whole grains). fortified) from dairy foods. They used a statistical model to focus on dairy consumption regardless of other factors such as non-dairy calcium intake, family history of prostate cancer, race or age. work.

The nature of such a large, diverse group, says Fraser, has put the study authors in a strong position to assess these differences. “Because our research group showed large disparities and differences in milk intake and calcium levels, we were able to question the level of unusual strength.”

One interesting factor to keep in mind, says Fraser, is The results did not show a uniformly increased risk in men who ate more milk. In other words, increasing milk intake by 50-gram servings did not confer the same increased risk as servings became larger.

“Most of the risk of continuing to increase is done when you get up to 150 grams, which is about two-thirds of a cup of milk a day,” says Fraser. “It’s almost as if some biological or biochemical pathway is saturated in about two-thirds of a cup of milk a day.”

Previous studies may have overlooked a curve effect or unevenly increased risk between dairy consumption and prostate cancer if most of those participants had been drinking more than one cup of milk per day. . However, the cohort of this study allowed researchers to compare dairy consumption across a wide range, including very low levels.

The data provide little evidence of an association between calcium intake and prostate cancer incidence. To promote overall prostate health and its proper functioning you can take prostate health supplements like Prostate Plus.

Fraser said a possible reason for the link between prostate cancer and dairy could be the sex hormone content in the milk. Up to 75% of lactating dairy cows are pregnant, and prostate cancer is a hormone-responsive cancer. Furthermore, previous reports suggest that the consumption of milk and other animal proteins is associated with higher blood levels of the hormone insulin-like growth factor-1 (IGF-1), which is believed to have promoter effects on some cancers, including prostate.

An earlier study from the Adventist Health Study-2 on The impact of milk on breast cancer risk in women has reported similar results both risk is not consistent with increased consumption and level of risk, Fraser said.

“The similarity between our article about breast cancer in women from a year ago and this article involving men is striking,” he said. “It seems the same biological mechanisms are at work.” However, Fraser said the study has not yet shown exactly that dairy causes prostate cancer.

As further studies investigate how dairy consumption may increase prostate cancer risk, Fraser advises that cautious men with a family history of prostate cancer or Other risk factors would be “cautious” about moderate dairy consumption in their diet until clarified.

“If you think you’re at higher-than-average risk, consider soy, oat, cashew, and other dairy-free alternatives,” he said.

The study is part of the Adventist Health Study-2, a long-term health study that explores links between lifestyle, diet, and disease among members of the Christian church. Easter. Adventist Health Research is funded in part through the benevolence of the Ardmore Health Institute.

Source: Eurekalert

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