Drugs with CBD show promise in post-surgery pain relief
“lead investigator Michael J. Alaia from NYU Langone Health.
“It could be a new, inexpensive approach to pain relief and without the side effects of anti-inflammatory drugs like NSAIDs and the addiction risk associated with opiates. Additionally, CBD has pain-relieving benefits without the psychotropic effects associated with THC or marijuana“, Alaia added.
For the study, presented at the 2022 Annual Meeting of the American Academy of Orthopedic Surgeons (AAOS) in Chicago, the multicenter phase 1/2 clinical trial randomized 99 people participants across two study sites between the ages of 18 and 75 in a placebo group. and one group received orally absorbed CBD.
Participants were given a low dose of Percocet, instructed to quit as soon as possible, and took a placebo/CBD three times a day for 14 days after surgery.
On the first day after surgery, patients taking CBD experienced an average of 23% less pain as measured by the Visual Analog Scale (VAS) pain scale compared with patients receiving placebo, highlighting that in patients with moderate pain, CBD can bring significant benefits.
On both the first and second day after surgery, patients taking CBD reported 22 to 25% greater satisfaction with pain control than those taking a placebo.
Further analysis also showed that patients taking 50 mg of CBD reported lower pain levels and higher levels of satisfaction with pain control than patients taking placebo. No major side effects were reported.