Experts warn omicron’s COVID variant could go undetected in the US
Fear of the omicron variant of the coronavirus spread across the globe within days of its discovery, send messy stock, travel restriction reminder and drew international attention to the rise in cases in South Africa.
The international response was many weeks faster than the slow response to the delta variant. By the time delta was called a “variant of concern” by the World Health Organization in May 2021, it had been spreading in India for months and had been cultivated globally.
In contrast, omicrons were first reported to WHO on Tuesday when COVID-19 infections in South Africa spiked to thousands per day. By Friday, it had been named and labeled a “worrying variant,” the most severe of its kind.
Given the high number of omicron mutations, experts have raised unanswered questions about the risk of reinfection for people who have been vaccinated or previously infected with other variants.
Experts have applauded the WHO for moving quickly to sound the alarm on the omicron and South Africa for its prompt, transparent reporting on this variation.
That should begin studies in the next few weeks into its transmissibility, virulence and “immunological escape capacity”, i.e. its ability to fight an immune response from previous infections or from vaccines. -Please, emergency physician and professor of public health at George Washington University, Dr. Leana On.
“The alarm level at this point is completely appropriate,” Wen told USA TODAY. “I’d rather we take action and then find out that, actually, this variant responds very well to the vaccines we have.”
Experts say that the initial data is difficult but incomplete.
According to Dr. Eric Topol, vice president of research at Scripps Research in La Jolla, California, the outbreak of omicron variation in South Africa resembles a “vertical line”.
“We haven’t seen anything like it,” he told USA TODAY. “The line of the slope is much higher than the original plain.”
Topol said the number of mutations associated with the virus could make it more contagious than previous variants, and it is likely that it developed in an immunocompromised person.
Also in the news:
► The CDC has issued a level 4 advisory, the highest level, due to “very high” COVID levels in eight African countries, a level that carries the “avoid travel” designation. Foreign Office also raise countries to level 4, which means “don’t travel.”
► WHO says it omitted two letters of the Greek alphabet – Nu and Xi – in naming the new variant omicron because Nu is too easily confused with the word “new” and because Xi is a common surname variable, according to a statement from the cave.
► The CDC this week reduced the proportion of adults vaccinated in Pennsylvania by nearly 5 percentage points, from 73.7% to 68.9%, in what is apparently a data adjustment to eliminate cases duplicate.
►The World Trade Organization is postponing the government ministerial conference scheduled to open on Tuesday after Switzerland began new travel restrictions following the arrival of the omicron.
►Stocks fell on Friday, with the Dow Jones Industrial Average briefly falling more than 1,000 points, as investors reacted to the omicron news.
📈Today’s Number: The United States has recorded more than 48 million confirmed COVID-19 cases and more than 776,000 deaths, according to data from Johns Hopkins University. Global total: Over 260.9 million cases and over 5.1 million deaths. More than 196.1 millionAmericans – about 59% of the population – are fully immunized, According to CDC.
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Omicron cases found in UK, Canada, other countries
Even with the quick response to news about omicrons, cases have been reported in travelers in Italy, Germany, France, Belgium, Israel, Hong Kong, Canadaand United Kingdom.
UK Health Secretary Sajid Javid on Saturday confirmed that two people tested positive for the omicron variant in Nottingham and Chelmsford, a town in southeastern England. He added the cases involved travel from southern Africa.
In Germany, the Max von Pettenkofer Institute, a microbiology center based in Munich, said the omicron variant had been confirmed in two travelers arriving on a flight from South Africa on November 24.
The French Ministry of Health announced eight possible cases of the Omicron variant on Sunday. Two cases were discovered in Canada after travelers returned from Nigeria, according to the Ontario government.
Authorities in the Netherlands are working to see if 61 people who tested positive for COVID-19 after arriving on flights from South Africa had the omicron variant. The Czech Republic also detected a suspected case of omicrons in a person living in Namibia, The Guardian reported.
An Italian man who had previously traveled to Mozambique on business landed in Rome on 11 November and returned to his home near Naples. He and five family members all tested positive, and the omicron variant was confirmed by the Sacco hospital in Milan. The man was vaccinated, the Italian National Institutes of Health said.
Dr. Eric Topol told USA TODAY, a concern echoed by the president’s medical adviser, Dr. Anthony Fauci. in a Saturday NBC interview.
“We haven’t detected it yet, but when you have a virus that’s showing this level of transmission and you’re having the travel-related cases they’ve documented elsewhere, when you get a virus like this, it’s pretty much invariable, Fauci said.
Fauci called President Joe Biden’s decision to restrict travel from South Africa and other countries in the region “cautious” and told Americans not to panic but to take this variant seriously when Health professionals learn more about omicrons.
He also called for vaccination, adding that booster shots offer a “very, very important advantage” in stopping the virus, including potentially dangerous variants.
Scientists await answers to important questions about omicron variation…
… Including important questions that remain unanswered.
Ashish K. Jha, Dean of the School of Public Health at Brown University, note three metrics to gauge the potential impact of a variation in a Twitter thread: if the new variant is more contagious than the currently dominant one, if it causes more severe disease, and if it will cause previous infections or vaccines to be less effective.
All of these questions remain largely unanswered, although Jha said it’s “very unlikely” that this variant would render the vaccine useless.
Experts say it could take weeks to see if current vaccines are less effective against omicrons. Epidemiologist Céline Gounder estimates it could take about two weeks to make this decision.
Gounder said in a Twitter thread that scientists still don’t know how omicron compares to delta in terms of its infectivity and incubation period.
What is happening in South Africa as omicrons spread?
In two weeks, South Africa has gone from a low transmission rate to a rapidly increasing rate of new cases. The spike in cases comes after a group of university students in Pretoria, one of the country’s capital cities, surged into the hundreds and then thousands, spreading to Johannesburg, the South’s largest city. Fly.
The new variant is likely to cause up to 90% of new cases, according to South African health officials, scientists say.
This variant also rapidly infects young South Africans, reflecting a shift in the demographic profile of COVID-19 patients.
Rudo Mathivha, head of the intensive care unit at Soweto’s Baragwanath Hospital, said in an online press conference: “Young people in their 20s to 30s, are suffering from moderate to severe illness, several illnesses. need special care. Some are vaccinated, but a few are fully vaccinated, Mathivha said.
Although the country’s case count remains relatively low with 2,828 new cases confirmed on Friday, Mathivha urged hospitals to have critical care beds ready in the event of a “worst-case scenario” that omicrons have. same effect as delta.
Mathivha also encourages vaccination. About 40% of South African adults are currently vaccinated, and vaccination rates among young people are lower.
Omicron’s impact on vaccines is unclear, but contingency plans will be in place
Health experts say it may be weeks before the world has good data on how omicrons can reduce the effectiveness of current vaccines, but Moderna has announced a three-point strategy to combat new variant.
Moderna says its strategy to respond to omicrons involves three options for boosting COVID-19 vaccination, should this variant prove problematic for current vaccines.
Three options, according to a Friday release from the company: Higher-dose, injections are currently being studied that are designed to “predict mutations, such as those already present in omicron variant” and an omicron-specific enhancer – which is already in the works.
Andy Slavitt, who previously served as a senior Biden White House adviser on the COVID response, said in a tweet that both Moderna and Pfizer-BioNTech have estimated a vaccine to fight a new variant has could be developed in about 3 months, with some regulatory and logistical pain to follow.
“If we start in early December, the new vaccine could be available by summer in most of the world,” Slavitt tweeted.
Multiple media organizations on Friday reported that Pfizer-BioNTech is working on a new variant and expects to have data within a few weeks. Reports say that, if warranted, a targeted vaccine could be developed within six weeks and shipped within 100 days.
Johnson & Johnson is also testing its current vaccine against omicrons, according to CNBC.
Professor Andrew Pollard, director of the Oxford Vaccine Group, told BBC Radio he was optimistic that the existing COVID vaccine would be effective in preventing serious illness from the omicron variant, adding that the mutations in the omicron appear to be in regions similar to mutations in other variants.
“That tells you that despite the mutations that exist in other variants, the vaccine continues to prevent serious disease as we move through,” said Pollard, whose team developed the AstraZeneca vaccine. alpha, beta, gamma and delta,” said Pollard, whose team developed the AstraZeneca vaccine. “At least from a speculative point of view, we have some optimism that the vaccine will still work against a new variant of the serious disease but really we need to wait a few weeks for that to happen.” confirm.”
– Joel Shannon, USA TODAY & The Associated Press
With omicron determination, are there more travel restrictions ahead?
Just when things were looking up for airlines and the rest of the travel industry, another COVID-19 variant emerged. Initial reports of the omicron variation immediately sparked travel restrictions.
The United States, which lifted a pandemic-spanning travel ban for dozens of international countries including South Africa on November 8, will on Monday replace the ban on foreign nationals from eight African country.
The CDC has issued a level 4 advisory, the highest level, due to “very high” COVID-19 levels, a level that specifies “avoid travel”. The State Department, which has general COVID-19 advisories in tandem with the CDC, also raised countries to level 4, which means “do not travel”.
“We will be cautious, ensuring that there is no travel to and from South Africa and the six other countries in that region. Except for those US citizens who can return,” Biden said Friday.
Read more about what travelers need to know about new restrictions and the potential impact on travel in the coming months if the omicron variant spreads rapidly globally.
– Dawn Gilbertson, USA TODAY
Contribution: Associated Press