Factors behind breast cancer recurrence discovered!

Breast cancer recurrence can be predicted through newly discovered factors according to a study at Georgetown University Medical Center, published in Scientific reports.

Research on breast epithelial cells (the layer of cells that form the ducts and lobules that make milk during breastfeeding) paves the way for stopping a new tumor from growing. The team specifically focused on the RNA sequence in a cell – the transcription system (which helps determine whether a gene is turned on or off in a cell).

“The risk of breast cancer recurrence in women can now be determined through genetic and other factors.”

It is seen that there are significant changes in genes (altered RNA) of women who received chemotherapy before surgery – prognostic indicators for cancer.

“When a person is diagnosed with breast cancer, we have a number of tools, including testing for genes like BRCA1/2, to decide if they should have certain types of chemotherapy or just treatment. with hormones. But the tools we have are not as accurate as we would like. About one in eight women are diagnosed with breast cancer in developed countries. We hope that our findings. I will help lead to more accurate and targeted screening in the future, minimizing unnecessary procedures for women as we currently screen almost all women between the ages of 40 and 70, sometimes very aggressive,” Priscilla Furth, MD, professor of oncology and medicine at Georgetown Lombardi and corresponding author of the study.

Source: Medindia

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