The increasing prevalence of type 2 diabetes has a major impact on quality of life and is still considered a serious public health concern.
Few risk factors for type 2 diabetes are genetics, lifestyle and environmental factors. Recently, changes in gut microbiota composition have also been linked to type 2 diabetes.
Previous studies have reported differences in gut bacteria between healthy volunteers and those already diagnosed with type 2 diabetes.
To identify gut bacteria markers for type 2 diabetes, researchers conducted a longitudinal study on the composition of fecal bacteria. They used stool samples collected from a large, representative and unique Finnish population, FINRISK 2002.
Abundant health data from more than 5,000 participants were collected during sampling, and morbidity has been tracked for nearly 16 years. electronic health records.
This allows the identification of microbial biomarkers that predict type 2 . incidence Diabetes in healthy participants at baseline.
Six groups of bacteria from the family Lachnospiraceae and its close relatives were associated with an increased risk of developing type 2 diabetes during follow-up.
Despite genetic and lifestyle differences, these bacteria are strongly linked to the prevalence of type 2 diabetes across Finland. This includes people from East and West Finland.
These findings suggest that gut microbiota composition may modulate the link between dietary habits and type 2 diabetes. Gut bacteria may also be used to develop new therapeutic targets. for diabetes.
Healthy gut to prevent diabetes
In the gut, there are specific friendly bacteria, which help with digestion and maintain metabolic health. In people with type 2 diabetes, healthy bacteria such as lactobacillus and bifidobacteria are replaced by unhealthy bacteria. This happens because eat snackssedentary lifestyle and obesity.
Understanding the gut microbiota composition as one of the risk factors for type 2 diabetes could aid in the development of more effective treatments in the future.
Through a healthy lifestyleEating lots of green leafy vegetables and fruits, avoiding junk food will help delay the onset of type 2 diabetes. At the same time, the balance of gut bacteria can also be restored. The use of probiotics also helps to restore unhealthy gut microbiota to healthy microorganisms.
Authority to solve:
- Gut microbiota activity predicts risk of type 2 diabetes and metformin control in a large human cohort – (https://www.medrxiv.org/content/10.1101/2021.08.13.21262051v1.full)