High blood pressure during pregnancy increases the risk of heart disease

To investigate the relationship between gestational hypertension and the onset of CVD, researchers at Brigham followed 60,739 mothers with CVD after their first birth using data from the nurse health care II.

In doing so, they discovered that

women with HDP had a 63% higher rate of CVD events

compared with women with normal blood pressure during pregnancy.

The increased risk of CVD was not explained by shared risk factors, including pre-pregnancy body mass index, smoking, and parental history of CVD.

The researchers also found that much of the increased risk (64%) was due to later development of chronic hypertension, hypercholesterolemia, type 2 diabetes, and/or weight gain after the first birth. first.

These established CVD risk factors account for an even higher proportion of CVD risk in women with gestational hypertension (84%) than in those with preeclampsia (57%).

The researchers also found that

The overall relationship between HDP and CVD appears to be driven by the underlying relationships between preeclampsia and coronary heart disease, and between gestational hypertension and stroke.

“Women with a history of gestational hypertension or preeclampsia should be informed that they are at increased risk for cardiovascular events. Screening and prevention efforts in those with a history of hypertension. Pregnancy or pre-eclampsia should target the cardiovascular disease risk factors of chronic hypertension, says Jennifer J. Stuart, ScD, of the Division of Women’s Health, with hypercholesterolemia, type 2 diabetes, and type 2 diabetes. 2 and overweight/obese.

“We look forward to continuing to investigate strategies to reduce long-term cardiovascular risk after hypertensive pregnancy and to empower and equip these patients to improve their cardiovascular health over the years.” and decades after birth.”

Source: Eurekalert

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