How the brain can aid in novel therapy
Another particularly common problem that epilepsy patients face, especially those with medial temporal lobe epilepsy, or MTLE is
Nearly one-third of all patients affected by drug-resistant epilepsy may require surgery.
“Our study is the first to detail the presence of newborn neurons and immature versions of a related cell type, known as astroglia (helper cells). neurons), in patients with epilepsy, our findings provide surprising new insights into how immature astroglia may contribute to epilepsy — opening a new pathway unexplored path towards the development of new antiepileptic drugs for millions of people,” Michael Bonaguidi, associate professor of stem cell biology and regenerative medicine, gerontology, and biomedical engineering at USC.
“Existing epilepsy drugs tend to target neurons, so drugs that act on immature neurons could greatly expand options for patients with epilepsy.” A new class of drugs that can be combined with current medical and surgical strategies to control seizures without the need for aggressive surgical removal of parts of the brain could be extremely important for us. with learning, memory, and emotional regulation,” Liu, a professor of neurosurgery, neurology, and biomedical engineering, director of the USC Center for Neurological Rehabilitation and director of the USC Epilepsy Care Consortium.