How to reduce the risk of AKI when drinking coffee?

“We already know that regular coffee consumption is linked to the prevention of chronic and degenerative diseases including type 2 diabetes, cardiovascular disease and disease,” said Chirag Parikh of Johns Hopkins University School of Medicine. liver. “We can now add AKI risk reduction to caffeine’s growing list of health benefits.”

AKI is a sudden episode of kidney failure or kidney damage that occurs within hours or days. This causes waste products to build up in the blood, making it difficult for the kidneys to maintain the correct balance of fluids in the body.

AKI symptoms vary depending on the cause and may include too little urine leaving the body; swelling in the legs and ankles, and around the eyes; weariness; shortness of breath; bewilderment; nausea; chest; and in severe cases it can lead to convulsions or coma. This disorder is most commonly seen in hospitalized patients whose kidneys are affected by stress and medical and surgical complications.


Using data from the Community Atherosclerosis Risk Study, an ongoing survey of cardiovascular disease in four US communities, researchers evaluated 14,207 adults recruited from from 1987 to 1989 with an average age of 54. Participants were surveyed 7 times over a 24-year period. the number of 8-ounce cups of coffee they drank daily: 0, 1, 2 to 3, or more 3. During the survey period, 1,694 cases of acute kidney injury were recorded.

When taking into account demographic characteristics, socioeconomic status, lifestyle influences, and dietary factors, the risk of AKI was 15% lower for participants who drank any amount of coffee. compared to those who didn’t drink. When adjusting for other comorbidities such as blood pressure, body mass index (BMI), diabetes status, use of antihypertensive drugs, and kidney function, coffee drinkers remained at a low risk of developing AKI. 11% more than those who didn’t drink.

“We suspect that the reason coffee affects AKI risk could be because the bioactive compounds in combination with caffeine or caffeine itself improve perfusion and utilization,” said Parikh. oxygen in the kidney. “Good kidney function and tolerance to AKI – depend on a steady supply of blood and oxygen.”

According to Parikh, more studies are needed to determine the possible protective mechanisms of coffee drinking on the kidneys, especially at the cellular level. “Caffeine has been recognized to inhibit the production of molecules that cause chemical imbalances and excessive oxygen use in the kidneys. Perhaps caffeine helps the kidneys maintain a more stable system.”

Parikh and his colleagues note that additives in coffee such as milk, half-and-half, cream, sugar or sweeteners may also influence AKI risk and require further investigation. Additionally, they say that consumption of other caffeinated beverages, such as tea or soda, should be considered a possible confounding factor.

Source: Medindia

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