Health

Microbiology harmful versus good in immunotherapy


Harmful gut bacteria may be more important than helpful bacteria for all cancer patients undergoing immunotherapy, according to a study at Oregon State University, published in the journal Cancer. Natural medicine.

As a result, research indicates that melanoma (the most aggressive skin cancer) patients who receive therapy that helps their immune system destroy cancer cells respond to treatment differently depending on the type of cancer. microorganisms in their intestines.

‘Microorganisms that interfere with immunotherapy in cancer patients were found to have a greater effect on them when compared with beneficial microorganisms.’

Melanoma ranks as the fifth most common cancer with 100,000 new melanoma cases diagnosed in the United States next year, with more than 7,000 deaths according to the American Cancer Society.

“Our findings shed light on the highly complex interaction between the gut microbiome and cancer immunotherapy response, and establish a pathway for future studies. established many microorganisms and some of them are clearly correlated with the response to cancer immunotherapy Two microbiological markers – one is relatively heavy for species of the family Lachnospiraceae, the other is relatively severe for species of the family Streptococcaceae – with favorable and unfavorable clinical responses, respectively,” Andrey Morgun of OSU College of Pharmacy said.

The results show that Gut microbiota evolved as a dominant factor to respond to therapy.

Source: Medindia



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