Peptides vs. Retinol: A Guide on Which Ingredient to Use

Peptides are naturally occurring amino acids which are the constructing blocks used to make proteins in our pores and skin, explains Joyce Imahiyerobo-Ip, MD, FAAD, founder and CEO of Vibrant Dermatology and Skin Bar MD. “Collagen, for instance, is made up of three polypeptide chains,” she says. “Including peptides to skincare merchandise has many advantages, together with stimulating collagen manufacturing, bettering pores and skin barrier perform, bettering pores and skin’s elasticity, and lowering irritation within the pores and skin.”

And never all peptides are the identical, there are differing kinds utilized in skincare. Tiffany Libby, MD, FAAD, Reserveage’s resident dermatologist, says when utilized topically, the peptides act as little messengers and instruct the pores and skin cells to carry out features like constructing collagen and elastin, reducing inflammation, and sustaining hydration.

“The primary teams are signaling peptides, enzyme-inhibiting peptides, provider peptides, and neurotransmitter-inhibiting peptides,” Libby says. “Signaling peptides work to stimulate new collagen and elastin manufacturing. Enzyme-inhibitor peptides block the enzymes that break down or degrade collagen. Provider peptides ship minerals to the pores and skin which are important for particular enzymatic processes like cross-linking collagen and wound therapeutic. Neurotransmitter inhibitor peptides work equally to neurotoxins like Botox, however with decrease efficacy to scale back wrinkle formation.”

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