© Reuters. FILE PHOTO: Pfizer emblem is mirrored in a drop on a syringe needle on this illustration photograph taken March 16, 2021. REUTERS/Dado Ruvic/Illustration
(Reuters) -Pfizer Inc mentioned on Monday it has began a big examine testing its investigational oral antiviral drug for the prevention of COVID-19 an infection amongst those that have been uncovered to the virus.
The drugmaker and its rivals, together with U.S.-based Merck & Co Inc and Swiss pharmaceutical Roche Holding AG (OTC:), have been racing to develop an easy-to-administer antiviral tablet for COVID-19.
The mid-to-late-stage examine will take a look at Pfizer (NYSE:)’s drug, PF-07321332, in as much as 2,660 wholesome grownup individuals aged 18 and older who dwell in the identical family as a person with a confirmed symptomatic COVID-19 an infection.
Within the trial, PF-07321332, designed to dam the exercise of a key enzyme wanted for the coronavirus to multiply, will probably be administered together with a low dose of ritonavir, an older medicine extensively utilized in mixture remedies for HIV an infection.
So far, Gilead Sciences Inc (NASDAQ:)’s intravenous drug remdesivir is the one authorised antiviral remedy for COVID-19 in the USA.
Pfizer has additionally began one other examine of PF-07321332 in non-hospitalized, symptomatic grownup sufferers.
Merck and accomplice Ridgeback Biotherapeutics lately launched a late-stage trial of their experimental drug molnupiravir for prevention of the COVID-19 an infection.
Molnupiravir can be being studied in a late-stage trial in non-hospitalized sufferers to see if it reduces the chance of hospitalization or dying.
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