Study finds that J&J Covid vaccine enhances immune response after Pfizer vaccination

Their small study of 65 volunteers who were initially given two doses of Pfizer / BioNTech’s vaccine found that using the J&J Janssen vaccine as a booster induces a slower antibody response. but more durable against the original strain, as well as Delta and Beta. they say.

The vast majority of Republicans do not want to strengthen

Their research shows that the Pfizer/BioNTech booster produces a faster and stronger immune response, with a faster drop.

“Both vaccines raised antibody titers very well. At week 4, neutralizing antibody levels were similar,” said Dr. Dan Barouch of Beth Israel Deaconess Medical Center and Harvard Medical School, who led the team, told CNN.

But after four weeks, antibody levels began to decrease in those boosted with the Pfizer vaccine while continuing to rise in those given the J&J vaccine. J&J’s vaccine also increases the number of immune cells called CD8 T cells.

All vaccinated adults should get a Covid-19 booster vaccine because of the Omicron variant, CDC says

Antibodies are a first line of immune defense that can prevent viruses from infecting cells, while T cells enter later and destroy infected cells. This T-cell protection doesn’t prevent mild infections, but can prevent them from progressing to serious illness.

While the study did not include the Omicron variant, Barouch said the findings could be important for figuring out how to combat the latest variant.

“For variants like Omicron that can partially evade antibody responses, CD8 T-cell responses may be particularly relevant for protection,” he said. “We think they are related in general but they could become particularly relevant if a variant emerges that can largely escape the antibodies.”

“Now we don’t know that for sure about Omicron, but as I’m sure you know, there’s a lot of concern or speculation that it could lead to at least some degree, possibly a remarkable degree. Well, get rid of the vaccine. make the antibodies. For a boost, you want a boost to increase both the antibody’s and the T-cell’s response.”

Barouch said his team submitted the findings to a peer-reviewed journal and in the meantime it was published online, without peer review, on preprint server MedRxiv.


Source link


News7h: Update the world's latest breaking news online of the day, breaking news, politics, society today, international mainstream news .Updated news 24/7: Entertainment, the World everyday world. Hot news, images, video clips that are updated quickly and reliably

Related Articles

Back to top button