Study reveals exact dose of UV sterilization against COVID-19
The idea for the study came as shortages of personal protective equipment (PPE) early in the pandemic prompted Ye University staff, Germany, and Binghamton to quickly build UV disinfection stations for children. hospitals in the area so that N-95 masks and other items can be reused.
“There are many studies on UV dosage in the scientific literature, but not systematically“Ye said.”When we started this project, there were really no data or experiments to do because the pandemic happened so quickly.. “
Ye and German received funding to pursue their questions through a mid-2020 grant of $182,728 from the National Science Foundation.
The Binghamton team added a retrovirus similar to SARS-CoV-2 to three different media and exposed them to three different wavelengths in the UVC range.
UVC destroys viruses and other microorganisms by damaging their DNA and RNA, which are biological organic building blocks for life.
“The effectiveness of sterilization is greatly affected by the media where the virus is located, Ye said. , but the effect is completely different. “
The best results during the study were the range of 260 to 280 nanometers, commonly used in UVC LEDs. Wavelengths below 260 nanometers can only be deployed in open spaces because they can be harmful to human skin and eyes.
“There are many companies that are deliberately saying that their products are completely disinfected and completely safe“, said Germany.
“However, in this paper, we demonstrate that both far (222 nanometers) and conventional (254 nanometers) UVC light degrades the mechanical integrity of the stratum corneum, the top layer of the skin, causing higher chance of cracking. That means nasty bacteria and other microorganisms can get in and potentially infect your skin.. “
Based on the research results, Ye and German designed a disinfection system using LED light, so there is less damage to human skin. They are conducting additional testing before filing a patent for it.
“We’re waiting for data, and then we’ve pretty much done. We know it will work“, Ye said.
Additionally, the Binghamton team also found that two amino acids and vitamins are strong UVC absorbers, and that discovery could lead to lotions that can block contact and prevent skin damage if UVC sterilization becomes more common in public spaces.
Ye believes that the most important part of this study is that it provides the scientific basis for standardizing and correcting the claims from UV sterilizer manufacturers.
“The system we devised can become a model for anyone who wants to standardize dosage“he say.”This is how to determine the level of eradication of SARS-CoV-2 by UVC – also SARS-CoV-3, SARS-CoV-4, SARS-CoV-5. We hope we never get there, but we need to prepare. “