Study says vitamin D deficiency is linked to severe COVID-19

This study is the first to analyze pre-infection vitamin D levels, providing a more accurate assessment than during hospitalization, when levels may be lower than secondary to viral illness. caused withdrawal.

The researchers searched the records of 1,176 patients hospitalized between April 2020 and February 2021 at Galilee Medical Center (GMC) with positive PCR tests for vitamin D levels measured from two weeks to two years before infection.

Patients with vitamin D deficiency (less than 20 ng/mL) were 14 times more likely to develop severe or critical COVID than patients over 40 ng/mL.

Notably, the mortality rate in patients with adequate vitamin D intake was 2.3%, in contrast to 25.6% in the vitamin D deficient group.

The study adjusted for age, sex, season (summer/winter), chronic illnesses, and found broadly similar results suggesting that low vitamin D levels contribute significantly to severity of illness. morbidity and mortality rates.

Dr. Amiel of the Galilee Medical Center and the Azrieli Faculty of Medicine at the University of Bar-Ilan, who led the study, said: “Our results suggest that vitamin D levels should be maintained.

“There is clear consensus on routine vitamin D supplementation as recommended by local health authorities as well as global health organizations.”

Dr Amir Bashkin, an endocrinologist involved in the current study, added that “This is especially true during the COVID-19 pandemic where adequate vitamin D has additional benefits for immune response. suitable for respiratory disease.”

Study co-author Professor Michael Edelstein said: “This study contributes to an continually growing body of evidence that a patient’s history of vitamin D deficiency is a predictive risk factor associated with vitamin D deficiency. poorer clinical course of COVID-19 and mortality.” Azrieli Faculty of Medicine of Bar-Ilan University.

“It remains unclear why some individuals suffer the severe consequences of contracting COVID-19 while others do not. Our findings add a new dimension to solving this puzzle.”


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