Symptoms of depression are tied to your ability to lead a full life

However, even without physical problems, individuals may report pain and fatigue that interferes with their daily activities, which is the case with depression.

A similar pattern between severity of depressive symptoms (i.e. low mood, loss of pleasure) and poor HRQL was observed in healthy, general population samples, suggesting that failure Having a diagnosis of a physical or emotional condition does not necessarily mean good health.

Studies have shown that the association between depressive symptoms and HRQL may be due to a common genetic etiology.

One method of discovering genetic etiology is the twin design, which estimates the extent to which genetic and environmental factors explain variation in depressive symptoms.

To explore further, a new study investigated the phenotypic and pathological relationships between depressive symptoms and HRQL and possible sex differences in a middle-income Sri Lankan population. short.

Data for 3,948 participants came from the Colombo Twin and Singleton Follow-up Study. Using self-report measures of depressive symptoms and HRQL, the researchers conducted the analysis.

The results showed that the unshared environment accounted for most of the variation in all HRQL offspring (ranged from 68 to 93%), along with small genetic influences (ranging from 0 to 23%). ) and general environmental effects (from 0 to 28 %).

Genetic influences are important for mental health (23%). Shared environmental influences were significant for four of the eight HRQL variables (ranging from 22-28%) and they were more prominent in women than in men..

Depressive symptoms were significantly associated with lower HRQL scores. These correlations are mainly explained by overlapping unshared environmental effects. For traits related to emotional functioning, significant overlapping genetic influences were detected.

This study confirmed previous findings of a negative association between depressive symptoms and HRQL. However, some of the etiological factors of HRQL differ from Western studies, especially on the impact of the shared environment.

These findings also highlight the importance of cross-cultural research in understanding the link between psychological well-being and HRQL.

Source: Medindia

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