The results showed a slight improvement in mental health in both groups, regardless of whether they were taking antidepressants.
Researchers from King Saud University, Saudi Arabia, call for more long-term studies of patients taking antidepressants to assess their impact on quality of life.
NHS doctors have abandoned prescribing the drug, which can cause a range of side effects.
The health service now recommends that patients with mild depression attend group therapy sessions before taking the medication.
But independent experts said it was not possible to draw firm conclusions from the study because people who were given the drug were more likely to be depressed at the start, and so it was not a fair comparison.
Their findings, published in the open access journal PLOS ONEshowed that antidepressant use was associated with some improvement in the mental composition of SF-12 – a health-related quality of life monitoring survey.
“Although we still need depressed patients to continue taking their antidepressants, long-term studies are needed to assess the actual impact of pharmacological and non-pharmacological interventions on quality of life. the lives of these patients.“Researchers led by Omar Almohammed from varsity said.
“With that said, the role of cognitive and behavioral interventions in the long-term management of depression needs further evaluation in an effort to improve the ultimate goal of care for these patients; improve their overall quality of life“he added.
During the study period, an average of 17.47 million adult patients were diagnosed with depression after two years of follow-up, and 57.6% of these were treated with antidepressants.
The study could not separately analyze any subtypes or different severity of depression. The team says that future studies should investigate the use of non-pharmacological depression interventions used in combination with antidepressants.